Melanocortin-4 Receptor Reporter Assay Kit

Melanocortin-4 Receptor Reporter Assay Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay600190-100 100 tests

1 - 10 business days

500.00€
 
The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and... more
Product information "Melanocortin-4 Receptor Reporter Assay Kit"
The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and inflammation. Mice deficient in MC4R have increased lipid deposition associated with elevated adiposity, while mutations in MC4R in humans are associated with early onset or severe obesity. This assay consists of a 96-well plate coated with a transfection complex containing DNA constructs for MC4R and a cAMP response element regulated Secreted Alkaline Phosphatase (SEAP) reporter (MC4R Reverse Transfection Strip Plate). Cells grown on the transfection complex will express MC4R at the cell surface. Binding of agonists to MC4R initiates a signal transduction cascade resulting in expression of SEAP which is secreted into the cell culture media. SEAP activity is measured following addition of a luminescence-based alkaline phosphatase substrate provided in the kit.
Supplier: Cayman Chemical
Supplier-Nr: 600190-1

Properties

Application: Reverse transfection reporter assay

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Melanocortin-4 Receptor Reporter Assay Kit"
Write a review
or to review a product.
Viewed