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Item number: BPS-60522
The Glucocorticoid Receptor Pathway Reporter Kit is designed for monitoring the activity of the glucocorticoid signaling pathway in cultured cells. The kit contains a transfection-ready expression vector for the glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4...
|Keywords:||GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1|
|Application:||Monitor glucocorticoid signaling pathway activity, Screening|
Item number: BPS-60601
PDE1B plays a key role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. PDE1B hydrolyzes both cAMP and cGMP to nucleoside 5'-monophosphate and prefers cGMP at low substrate levels.The PDE1B Cell-Based Reporter Assay Kit is designed for identification of PDE1B inhibitors in...
|Keywords:||PDE1B, PDE1B1, Cam-PDE 1B, EC=188.8.131.52, 63 kDa Cam-PDE, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide...|
|Application:||PDE1B inhibitor screening|
Item number: BPS-60612
The AP1 Reporter Kit is designed for monitoring the activity of the JNK signaling pathway and the transcriptional activity of AP1 in cultured cells. The kit contains a transfection-ready AP1 luciferase reporter vector. This reporter contains the firefly luciferase gene under the control of multimerized AP1...
|Keywords:||AP1, JUN, p39, Activator protein 1, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene...|
|Application:||JNK activity assays|
Item number: BPS-60613
The ISRE Reporter kit is designed for monitoring the activity of Type I interferon-induced JAK/STAT signaling pathway in the cultured cells. The kit contains transfection-ready ISRE luciferase reporter vector, which is a JAK/STATpathway-responsive reporter. This reporter contains a firefly luciferase gene under the...
|Keywords:||STAT2, STAT1, Transcription factor ISGF-3 components p91/p84, p113, Signal transducer and activator of transcription...|
|Application:||JAK/STAT pathway activity monitoring, Activator/inhibitor screening|