NIR-FLIVO(TM) 690 in vivo Apoptosis Kit (DyLight(R) 690-VAD-FMK), 20 tests

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ICT-9112 20 tests -

3 - 10 business days*

629.00€
 
NIR-FLIVO(TM)in vivo Apoptosis Kits provide an accurate and direct method to image apoptosis in... more
Product information "NIR-FLIVO(TM) 690 in vivo Apoptosis Kit (DyLight(R) 690-VAD-FMK), 20 tests"
NIR-FLIVO(TM)in vivo Apoptosis Kits provide an accurate and direct method to image apoptosis in vivo. With its ability to be imaged noninvasively, NIR-FLIVO(TM) 690 is a powerful imaging tool, allowing longitudinal studies and eliminating false positives that may arise from ex vivo manipulation of tissue. All FLIVO(TM)(FLuorescence in vIVO) tracers are non-cytotoxic fluorescent inhibitors of the class of cysteine proteases known as caspases, which are associated with the execution of apoptosis. After intravenous injection, the FLIVO(TM)tracers circulate throughout the body and preferentially form covalent bonds with active caspases, marking apoptotic cells with its fluorescent signal. The bound FLIVO(TM)tracer will remain inside the cell as long as the cell membrane is intact. Any unbound FLIVO(TM) is removed with the natural circulation of the animal. The resulting fluorescent signal within samples is a direct measure of apoptosis that was occurring at the time the reagent was injected. FLIVO(TM) is non-toxic, cell-permeant, and crosses the blood-brain barrier. Reagent titration experiments should be performed to determine the amount of reagent that will work best for the size of the animal and the target tissue type. Apoptosis detection with FLIVO(TM) provides a true representation of the induction of apoptosis as a result of the experimental condition. Applications: FLIVO(TM) may be used in animal models to monitor the efficacy of treatment or the effects of disease.
Keywords: Fluorescent inhibitor, Apoptosis tracer
Supplier: ImmunoChemistry Technologies
Supplier-Nr: 9112

Properties

Application: In vivo apoptosis detection
Format: Homog.

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Handling & Safety

Storage: vT
Shipping: vT (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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