These cookies are necessary for the basic functions of the shop.
Allow all cookies
Decline all cookies
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Conversion and usertracking via Google Tag Manager
Product information "Annexin V-AF647 / 7-AAD Apoptosis Detection Kit"
Elabscience Annexin V-AF647/7-AAD Cell Apoptosis Detection kit is developed to identify apoptotic and necrotic cells. Annexin V is a member of the annexin family, which binds to phosphatidylserine (PS) in a calcium-dependent manner. The fluorescent format of this intracellular protein, Annexin V-AF647, binds specifically to the PS on outer leaflet of cell membrane by flow cytometry or fluorescence microscopy. 7-AAD (7-amino-actinomycin D) has a high DNA binding constant and is efficiently excluded by intact cells. It is useful for DNA analysis and dead cell discrimination during flow cytometric analysis. Due to the loss of integrity of membrane, 7-AAD can enter late apoptotic or necrotic cells to stain DNA. Cells at different apoptotic stages can be distinguished by using Annexin V and 7-AAD.