Cell-Based Assays

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Melanocortin-4 Receptor Reporter Assay Kit
Melanocortin-4 Receptor Reporter Assay Kit

Item number: Cay600190-100

The melanocortin-4 receptor (MC4R) has important roles in weight regulation, sexual function, and inflammation. Mice deficient in MC4R have increased lipid deposition associated with elevated adiposity, while mutations in MC4R in humans are associated with early onset or severe obesity. This assay consists of a...
Application: Reverse transfection reporter assay
500.00€
Review
Orexin Receptor 1 STEP(TM) Reporter Assay Kit (Luminescence)
Orexin Receptor 1 STEP(TM) Reporter Assay Kit (Luminescence)

Item number: Cay600240-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 1 Receptor (OX1R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with...
Keywords: Ox1R, Ox1-R, Ox-1-R, HCRTR1, Orexin receptor type 1, Hypocretin receptor type 1
Application: OX1R activation assays
500.00€
Review
Orexin 2 Receptor Reporter Assay Kit
Orexin 2 Receptor Reporter Assay Kit

Item number: Cay600250-100

Surface Transfection and Expression Protocol (STEP(TM)) is a novel, patented, solid phase transient transfection technology that overcomes many of the disadvantages of other transfection approaches. CaymansOrexin 2 Receptor (OX2R) STEP(TM) Reporter Assay Kit (Luminescence) consists of a 96-well plate coated with...
Keywords: Ox2R, Ox2-R, Ox-2-R, HCRTR2, Orexin receptor type 2, Hypocretin receptor type 2
Application: OX2R activation assays
500.00€
Review
Secreted Alkaline Phosphatase Reporter Gene Assay Kit (Luminescence)
Secreted Alkaline Phosphatase Reporter Gene Assay Kit...

Item number: Cay600260-300

Secreted alkaline phosphatase (SEAP) is commonly used as a reporter of gene expression. Compared to other conventional intracellular reporters such as chloramphenicol acetyltransferase (CAT) and firefly luciferase, SEAP has the advantage of being secreted from transfected cells into the culture medium. Cayman's...
Keywords: SEAP Reporter Gene
Application: Chemiluminescence
287.00€
Review
Sulfenylated Protein Cell-Based Detection Kit
Sulfenylated Protein Cell-Based Detection Kit

Item number: Cay600320-96

Reactive oxygen species (ROS) react with proteins, resulting in protein modification, such as protein sulfenylation through the reversible oxidation of cysteine residues. Redox-sensitive cysteine residues in proteins can function as sensors of ROS and serve as molecular switches, activating or deactivating proteins,...
Keywords: Protein Sulfenylation Detection Kit, S-sulfenylated Protein Detection Assay
Application: FC, Fluorescence
407.00€
Review
EP2 Receptor (rat) Reporter Assay Kit
EP2 Receptor (rat) Reporter Assay Kit

Item number: Cay600340-1

The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various diseases. Cayman's EP2...
Keywords: Ptger2, Prostanoid EP2 receptor, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostaglandin E2 receptor EP2 subtype
Application: Reverse transfection reporter assay
Reactivity: Rat
500.00€
Review
EP4 Receptor (rat) Reporter Assay Kit
EP4 Receptor (rat) Reporter Assay Kit

Item number: Cay600350-100

The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various...
Keywords: Ptger4, Prostanoid EP4 receptor, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E2 receptor EP4 subtype
Application: Reverse transfection reporter assay
Reactivity: Rat
500.00€
Review
Glutathione Cell-Based Detection Kit (Blue Fluorescence)
Glutathione Cell-Based Detection Kit (Blue Fluorescence)

Item number: Cay600360-96

Glutathione (GSH) is the most prevalent low molecular-weight tripeptide thiol in animal cells. It serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During early apoptosis, cells may exclude GSH, causing a decrease in intracellular GSH levels. The...
Keywords: GSH Cell-Based Detection Kit (Blue Fluorescence)
Application: Fluorescence
332.00€
Review
Multi-Drug Resistance Assay Kit (Calcein AM)
Multi-Drug Resistance Assay Kit (Calcein AM)

Item number: Cay600370-1000

P-Glycoprotein (P-gp), the product of the multidrug resistance (MDR) gene MDR1, and multidrug resistance associated proteins (MRP) are members of the superfamiliy of ATP-binding cassette (ABC) transporters. They are localized in the luminal membrane of endothelial cells and function to detoxify or eliminate a...
Keywords: MDR
Application: MDR protein modulator studies
282.00€
Review
EP4 Receptor (rat) Activation Assay Kit (cAMP)
EP4 Receptor (rat) Activation Assay Kit (cAMP)

Item number: Cay600410-1

The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the function of this receptor subtype and for use as therapeutics for various...
Keywords: Ptger4, Prostanoid EP4 receptor, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostaglandin E2 receptor EP4 subtype
Application: Reverse transfection reporter assay
Reactivity: Rat
563.00€
Review
Cholesterol Uptake Cell-Based Assay Kit
Cholesterol Uptake Cell-Based Assay Kit

Item number: Cay600440-1

Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. However, the mechanisms controlling cholesterol absorption are not well understood. A better...
Application: FC
232.00€
Review
Glycolysis Cell-Based Assay Kit
Glycolysis Cell-Based Assay Kit

Item number: Cay600450-1

Cayman's Glycolysis Cell-Based Assay Kit provides a colorimetric method for detecting L-lactate, the end product of glycolysis, produced and secreted by cultured cells. In this assay, lactate dehydrogenase catalyzes the reaction between NAD+ and lactate, yielding pyruvate and NADH. The NADH directly reduces a...
Keywords: Glycolysis
Application: Extracellular L-lactate detection
313.00€
Review
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