Biochemical Assays

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p53 Transcription Factor Assay Kit
p53 Transcription Factor Assay Kit

Item number: Cay600020-96

The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA binding activity in nuclear extracts. A specific double-stranded...
Application: P53 detection
Format: Solid Phase
532.00€
Review
SET7/9 SAM-Screener(TM) Assay Kit
SET7/9 SAM-Screener(TM) Assay Kit

Item number: Cay600490-384

Most histone lysine methyltransferases contain a conserved domain (SET) that utilizes S-adenosyl-L-methionine (SAM or AdoMet) as a co-factor to catalyze the methylation of lysine. SET7/9 (KMT7) is a SET domain-containing mono-methyltransferase that acts on a large number of histone and non-histone targets including histone H3, TAF10, p53, viral Tat, and estrogen receptor...
Application: Fluorescence, HTS
Format: Homog.
From 469.00€
Review
GLP SAM-Screener(TM) Assay Kit
GLP SAM-Screener(TM) Assay Kit

Item number: Cay600570-384

Most histone lysine methyltransferases contain a conserved domain (SET) that utilizes S-adenosyl-L-methionine (SAM or AdoMet) as a co-factor to catalyze the methylation of the epsilon amino group of lysine. G9a-like protein (GLP) is a SET domain-containing methyltransferase that specifically mono- and di-methylates histone H3 at lysine 9 (H3K9). GLP and G9a function as major...
Application: Fluorescence, HTS
Format: Homog.
From 469.00€
Review
MLL1 SAM-Screener(TM) Assay Kit
MLL1 SAM-Screener(TM) Assay Kit

Item number: Cay600580-384

Most histone lysine methyltransferases contain a conserved domain (SET) that utilizes S-adenosyl-L-methionine (SAM or AdoMet) as a co-factor to catalyze the methylation of the epsilon amino group of lysine. Mixed-lineage leukemia (MLL1) is a member of the trithorax group (trxG)/Set1-like family of gene activators that contains histone methyltransferase activity specific for...
Application: Fluorescence, HTS
Format: Homog.
From 469.00€
Review
Nrf2 Transcription Factor Assay Kit
Nrf2 Transcription Factor Assay Kit

Item number: Cay600590-96

Nuclear factor E2-related factor 2 (Nrf2) is a transcription factor that plays a key role in maintaining redox homeostasis via its interaction with a cysteine-rich protein Kelch-like ECH-associated protein 1 (Keap1). In resting cells, Nrf2 and Keap1 form a tight complex, which is targeted for degradation by proteasomes. Under oxidative stress, Nrf2 is released from the...
Application: DNA binding assay
Format: Solid Phase
532.00€
Review
NETosis Assay Kit
NETosis Assay Kit

Item number: Cay601010-1

Cayman's NETosis Assay Kit provides a simple and fast method for studying the process of NETosis ex vivo. Notably, Cayman's NETosis Assay Kit does not depend upon the DNA component of neutrophil extracellular traps (NETs), as DNA release can occur independently of NETosis. In this kit, primary neutrophils are stimulated to release NETs with either PMA or a calcium ionophore...
Application: NET generation assay
Format: Misc.
388.00€
Review
Oct4 Transcription Factor Assay Kit
Oct4 Transcription Factor Assay Kit

Item number: Cay601080-96

Octamer-binding transcription factor 4 (Oct4) is an essential regulator of embryonic stem cell pluripotency and used as a marker for undifferentiated cells. It also plays a role in gene expression, DNA repair and/or replication, signal transduction and tumorigenesis. Cayman's Oct4 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific...
Application: Oct4 DNA binding assay
Reactivity: Mouse
Format: Solid Phase
532.00€
Review
Neutrophil/Monocyte Respiratory Burst Assay Kit
Neutrophil/Monocyte Respiratory Burst Assay Kit

Item number: Cay601130-1

Respiratory burst, or the rapid generation of reactive oxygen species from immune cells, is crucial for the destruction of invading microorganisms by phagocytes. During this process, professional phagocytes convert molecular oxygen to superoxide anions through the action of NADPH oxidase, which is then converted to reactive oxygen species with potent antimicrobial activity....
Application: FC
Reactivity: Broad
Format: Homog.
369.00€
Review
Multi-Parameter Apoptosis Assay Kit
Multi-Parameter Apoptosis Assay Kit

Item number: Cay601280-1

Cayman's Multi-Parameter Apoptosis Assay Kit is a simple way to probe for multiple different apoptotic readouts at the same time. This kit employs FITC-conjugated Annexin V as a probe for phosphatidylserine on the outer membrane of apoptotic cells, TMRE as a probe for Deltapsim, RedDotTM2 as an indicator of plasma membrane permeability/cell viability, and Hoechst Dye to...
Application: Cell based assays, FC, Fluorescence, Multiplex
Format: Homog.
438.00€
Review
EP2 Receptor (human) Reporter Assay Kit
EP2 Receptor (human) Reporter Assay Kit

Item number: Cay601380-96

Prostaglandin E2 (PGE2) is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4. These four G protein-coupled receptors (GPCRs) exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression. EP2 receptors are...
Application: Cell based assays, Chemiluminescence, HTS, Reverse transfection reporter assay
Format: Solid Phase
500.00€
Review
EP4 Receptor (human) Reporter Assay Kit
EP4 Receptor (human) Reporter Assay Kit

Item number: Cay601390-96

Prostaglandin E2 (PGE2) is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4. These four G protein-coupled receptors (GPCRs) exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression. EP4 receptors are highly...
Application: Cell based assays, Chemiluminescence, HTS, Reverse transfection reporter assay
Format: Solid Phase
500.00€
Review
Mitochondrial PT Pore Assay Kit
Mitochondrial PT Pore Assay Kit

Item number: Cay601430-100

Cayman's Mitochondrial PT Pore Assay Kit utilizes the calcein/cobalt technique multiplexed with TMRE, allowing for the measurement of both membrane integrity and mitochondrial membrane potential (Deltapsim). This assay has been adapted for use with flow cytometry and fluorescence microscopy, and includes controls for Deltapsim depolarization (FCCP) and calcein quenching...
Application: Cell based assays, FC, Fluorescence
Format: Homog.
525.00€
Review
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