Anti-Polyglutamylation Modification, clone GT335

Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-20B-0020-C100 100 µg -

3 - 9 business days*

10 %
451.00€
405.90€
 
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with... more
Product information "Anti-Polyglutamylation Modification, clone GT335"
Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved from and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and involved in cell cycle and cell proliferation.
Keywords: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20B-0020

Properties

Application: ICC, IP, WB, IHC (paraffin), IEM
Antibody Type: Monoclonal
Clone: GT335
Conjugate: No
Host: Mouse
Species reactivity: All
Immunogen: Octapeptide EGEGE*EEG, modified by the addition of two glutamyl units onto the fifth E (indicated by an asterik).
Format: Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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