Anti-phospho-TNFR1 (Ser274) (Tumor Necrosis Factor Receptor Superfamily Member 1A, Tumor Necrosis Fa

Anti-phospho-TNFR1 (Ser274) (Tumor Necrosis Factor Receptor Superfamily Member 1A, Tumor Necrosis Fa
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T9161-07H-Biotin.200 200 µl - -

3 - 19 business days*

993.00€
 
A member of the TNF-receptor superfamily, this protein is one of the major receptors for the... more
Product information "Anti-phospho-TNFR1 (Ser274) (Tumor Necrosis Factor Receptor Superfamily Member 1A, Tumor Necrosis Fa"
A member of the TNF-receptor superfamily, this protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-1:500, Immunohistochemistry: 1:50-1:100, Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-phospho-TNFAR, Anti-phospho-TNFRSF1A
Supplier: United States Biological
Supplier-Nr: T9161-07H-Biotin

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: Biotin
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser274 of human TNFR1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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