Anti-phospho-STAT2 (Tyr690)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-A93S 25 µl - -

1 - 9 business days

132.00€
600-401-A93 100 µg - -

1 - 9 business days

493.00€
 
Protein function: Signal transducer and activator of transcription that mediates signaling by... more
Product information "Anti-phospho-STAT2 (Tyr690)"
Protein function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [The UniProt Consortium]
Keywords: Anti-phospho-p113, Anti-phospho-STAT2, Anti-phospho-Signal transducer and activator of transcription 2
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-A93S

Properties

Application: ELISA, WB, IP
Antibody Type: Polyclonal
Conjugate: No
MW: 113 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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