Anti-phospho-Raptor (Ser863) (Regulatory-associated Protein of mTOR, Raptor, P150 Target of Rapamyci

Anti-phospho-Raptor (Ser863) (Regulatory-associated Protein of mTOR, Raptor, P150 Target of Rapamyci
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1170-02A-PE.200 200 µl - -

3 - 19 business days*

993.00€
 
Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1... more
Product information "Anti-phospho-Raptor (Ser863) (Regulatory-associated Protein of mTOR, Raptor, P150 Target of Rapamyci"
Raptor participates in the FRAP1 pathway and associates in a near stoichiometric ratio with FRAP1 to form a nutrient-sensitive complex (NSC). It plays a pivotal role as a scaffold protein in the FRAP1-signaling pathway and this interaction is essential for the catalyzed phosphorylation of EIF4EBP1. It has a positive role in nutrient-stimulated signaling to the downstream effector RPS6KB1. Under nutrient-deprived conditions, raptor serves as a negative regulator of FRAP1 kinase activity. Regulation of the interaction with FRAP1 is a critical mechanism by which cells coordinate the rate of cell growth and maintenance of cell size with different environmental conditions. Applications: Suitable for use in FLISA and Dot Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-phospho-RPTOR, Anti-phospho-Raptor, Anti-phospho-KIAA1303, Anti-phospho-Regulatory-associated protein of mTOR, Anti-phospho-p150 target of rapamycin (TOR)-scaffold protein
Supplier: United States Biological
Supplier-Nr: R1170-02A-PE

Properties

Application: FLISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: Phycoerythrin
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser863 of human Raptor (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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