Anti-phospho-RanBP3, (Ser58) (Ran-binding Protein 3)

Anti-phospho-RanBP3, (Ser58) (Ran-binding Protein 3)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1069-12.100 100 µl - -

4 - 22 business days

543.00€
 
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding... more
Product information "Anti-phospho-RanBP3, (Ser58) (Ran-binding Protein 3)"
Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export. [The UniProt Consortium]
Keywords: Anti-phospho-RanBP3, Anti-phospho-RANBP3, Anti-phospho-Ran-binding protein 3
Supplier-Nr: R1069-12

Properties

Application: IP, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Monkey
Immunogen: Synthetic peptide corresponding to residues surrounding Ser58 of human RanBP3b.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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