Anti-phospho-PI3KC3 (Ser676) (Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, PtdIns-3-kinas

Anti-phospho-PI3KC3 (Ser676) (Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, PtdIns-3-kinas
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P4073-33N-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme... more
Product information "Anti-phospho-PI3KC3 (Ser676) (Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, PtdIns-3-kinas"
PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway. Applications: Suitable for use in FLISA and Dot Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-phospho-VPS34, Anti-phospho-hVps34, Anti-phospho-PIK3C3, Anti-phospho-PI3K type 3, EC=2.7.1.137, Anti-phospho-PI3-kinase type 3, Anti-phospho-PtdIns-3-kinase type 3, Anti-phospho-Phosphoinositide-3-kinase class 3
Supplier: United States Biological
Supplier-Nr: P4073-33N-APC

Properties

Application: FLISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser676 of human PI3KC3 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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