Anti-phospho-phospho-IL-7RA, (Tyr449) (Interleukin-7 Receptor Subunit alpha, IL-7 Receptor Subunit

Anti-phospho-phospho-IL-7RA, (Tyr449) (Interleukin-7 Receptor Subunit alpha, IL-7 Receptor Subunit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
I8429-27N2.50 50 µg - -

1 - 19 business days

713.00€
 
Interleukin 7 Receptor (IL7R) is a receptor for interleukin 7 (IL7). The function of IL7R... more
Product information "Anti-phospho-phospho-IL-7RA, (Tyr449) (Interleukin-7 Receptor Subunit alpha, IL-7 Receptor Subunit"
Interleukin 7 Receptor (IL7R) is a receptor for interleukin 7 (IL7). The function of IL7R requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution:y: ELISA: 1:100,000 , Western Blot: 1:1000-1:10,000, Immunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: I8429-27N2

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Mouse
Immunogen: Synthetic peptide corresponding to residues near Y449 of mouse IL-7 protein.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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