Anti-phospho-PARP1 (Ser274) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransfer

Anti-phospho-PARP1 (Ser274) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransfer
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039669.200 200 µl - -

1 - 19 business days

557.00€
 
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies... more
Product information "Anti-phospho-PARP1 (Ser274) (PARP1, ADPRT, PPOL, Poly [ADP-ribose] polymerase 1, ADP-ribosyltransfer"
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. Applications: Suitable for use in Dot Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Dot blot 1:500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-phospho-ADPRT, Anti-phospho-ARTD1, Anti-phospho-PARP1, Anti-phospho-PARP-1, Anti-phospho-ADPRT 1, EC=2.4.2.30, Anti-phospho-Poly[ADP-ribose] synthase 1, Anti-phospho-Poly [ADP-ribose] polymerase 1, Anti-phospho-NAD(+) ADP-ribosyltransferase 1
Supplier: United States Biological
Supplier-Nr: 039669

Properties

Application: ELISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Phospho-PARP1-S274 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S274 of human PARP1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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