Anti-phospho-Myc (Thr58)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-35-1033-50 50 µl -

3 - 11 business days*

574.00€
 
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet... more
Product information "Anti-phospho-Myc (Thr58)"
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed:20010808). [The UniProt Consortium]
Keywords: Anti-phospho-MYC, Anti-phospho-bHLHe39, Anti-phospho-BHLHE39, Anti-phospho-Proto-oncogene c-Myc, Anti-phospho-Transcription factor p64, Anti-phospho-Myc proto-oncogene protein, Anti-phospho-Class E basic helix-loop-helix protein 39, Polyclonal Antibody to
Supplier: Abeomics
Supplier-Nr: 35-1033-50

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Peptide sequence around phosphorylation site of threonine 58 (L-P-T(p)-P-P) derived from Human Myc.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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