Anti-phospho-MCM2 (Ser41)

Anti-phospho-MCM2 (Ser41)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG40913.100 100 µl - -

6 - 14 business days*

505.00€
 
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative... more
Product information "Anti-phospho-MCM2 (Ser41)"
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis. [The UniProt Consortium]
Keywords: Anti-phospho-MCM2, Anti-phospho-BM28, EC=3.6.4.12, Anti-phospho-Nuclear protein BM28, Anti-phospho-DNA replication licensing factor MCM2, Anti-phospho-Minichromosome maintenance protein 2 homolog
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG40913

Properties

Application: ICC, IF, IHC (paraffin), IP, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Phosphospecific peptide around Ser41 of Human MCM2
MW: 102 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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