Anti-phospho-Hamartin, (S505) (TSC1, Tuberous Sclerosis 1 Protein, KIAA0243, TSC)

Anti-phospho-Hamartin, (S505) (TSC1, Tuberous Sclerosis 1 Protein, KIAA0243, TSC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
H1779-01G.200 200 µl - -

3 - 19 business days*

728.00€
 
TSC1 is implicated as a tumor suppressor, and may have a function in vesicular transport.... more
Product information "Anti-phospho-Hamartin, (S505) (TSC1, Tuberous Sclerosis 1 Protein, KIAA0243, TSC)"
TSC1 is implicated as a tumor suppressor, and may have a function in vesicular transport. Interaction between TSC1 and TSC2 may facilitate vesicular docking Defects in TSC1 are the cause of tuberous sclerosis complex (TSC). The molecular basis of TSC is a functional impairement of the hamartin-tuberin complex. TSC is an autosomal dominant multi-system disorder that affects especially the brain, kidneys, heart, and skin. Defects in TSC1 may be a cause of focal cortical dysplasia of Taylor balloon cell type (FCDBC). FCDBC is a subtype of cortical displasias linked to chronic intractable epilepsy. Cortical dysplasias display a broad spectrum of structural changes, which appear to result from changes in proliferation, migration, differentiation, and apoptosis of neuronal precursors and neurons during cortical development. Applications: Suitable for use in ELISA and Dot Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-phospho-Tuberous sclerosis 1 protein
Supplier: United States Biological
Supplier-Nr: H1779-01G

Properties

Application: ELISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding S505 of human TSC1 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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