Anti-phospho-Fanconi anemia D2, (Ser222) (FA4, FACD, FAD, FAD2, FANCD2, Fanconi anemia Comple

Anti-phospho-Fanconi anemia D2, (Ser222) (FA4, FACD, FAD, FAD2, FANCD2, Fanconi anemia Comple
Item number Size Datasheet Manual SDS Delivery time Quantity Price
F0019-58W5.200 200 µl - -

3 - 19 business days*

688.00€
 
Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized... more
Product information "Anti-phospho-Fanconi anemia D2, (Ser222) (FA4, FACD, FAD, FAD2, FANCD2, Fanconi anemia Comple"
Fanconi anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANCD2, targeting nuclear foci containing the BRCA1 protein. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: F0019-58W5

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: A synthetic peptide made to the human FANCD2 sequence (residues 217-226), surrounding a phosphorylated serine (222).
Purity: Serum
Format: Serum

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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