Anti-acetyl-Tubulin, alpha (Lys40) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, T

Anti-acetyl-Tubulin, alpha (Lys40) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, T
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T9154-01C.100 100 µl - -

1 - 19 business days

581.00€
 
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin... more
Product information "Anti-acetyl-Tubulin, alpha (Lys40) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, T"
The cytoskeleton consists of three types of cytosolic fibers: microtubules, microfilaments (actin filaments), and intermediate filaments. Globular tubulin subunits comprise the microtubule building block, with alpha/beta-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. Gamma-tubulin is necessary to nucleate polymerization of tubulin subunits to form microtubule polymers. Many cell movements are mediated by microtubule action, including the beating of cilia and flagella, cytoplasmic transport of membrane vesicles, chromosome alignment during meiosis/mitosis, and nerve-cell axon migration. These movements result from competi-tive microtubule polymerization and depolymerization or through the actions of microtubule motor proteins (1). The Elongator complex catalytic subunit (Elp3) acetylates alpha-tubulin at Lys40 while the histone deacetylase HDAC6 functions as a tubulin deacetylase. This post-transcriptional modification may be required for dynamic cell shape remod-eling, cell motility, tubulin stability and terminal branching of cortical neurons (2,3). Applications: Suitable for use in Immunofluorescence, Immunoprecipitation, Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Immunofluorescence (IC): 1:800, Immunoprecipitation: 1:50, Western Blot: 1:1000 Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight., Flow Cytometry: 1:200, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-acetyl-TUBA1B, Anti-acetyl-Tubulin K-alpha-1,Anti-acetyl-Alpha-tubulin ubiquitous, Anti-acetyl-Tubulin alpha-ubiquitous chain
Supplier: United States Biological
Supplier-Nr: T9154-01C

Properties

Application: IF, IP, WB
Antibody Type: Monoclonal
Clone: 10E52(D20G3)
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat, Zebrafish
Immunogen: A synthetic acetylpeptide corresponding to residues surrounding Lys40 of human alpha-tubulin (KLH).
Format: Supernatant

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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