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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay13726-400 | 400 µl | - |
6 - 10 business days* |
595.00€
|
Post-translational modifications of proteins play critical roles in the regulation and function... more
Product information "Anti-Acetyl Lysine HRP Conjugate"
Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways, and a common post-transcriptional modification of lysine involves acetylation. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Protein post-translational reversible lysine Nepsilon-acetylation and deacetylation have been recognized as an emerging intracellular signaling mechanism that plays critical roles in regulating gene transcription, cell-cycle progession, apoptosis, DNA repair, and cytoskeletal orgnization. The regulation of protein acetylation status is impaired in the pathologies of cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.Immunogen: Acetylated KLH. Formulation: (Request formulation change), 400 µl of protein A-affinity purified polyclonal antibody. Storage Buffer: PBS with 50% glycerol and 0.09% sodium azide. Host: Rabbit. Applications: ELISA, ICC, IF, IP, and WB. Cross Reactivity: (-) Non-acetylated proteins. Origin: Animal/Rabbit.
Supplier: | Cayman Chemical |
Supplier-Nr: | 13726 |
Properties
Application: | WB, IP, ELISA, IF |
Antibody Type: | Polyclonal |
Conjugate: | HRP |
Host: | Rabbit |
Immunogen: | acetylated KLH |
Format: | Solution |
Database Information
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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