SSX2IP Antibody AbVantage(TM) Pack

SSX2IP Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A311-216A 1 pack -

3 - 9 business days

598.00€
 
Protein function: Belongs to an adhesion system, which plays a role in the organization of... more
Product information "SSX2IP Antibody AbVantage(TM) Pack"
Protein function: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin. Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling. Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). [The UniProt Consortium]
Keywords: Anti-ADIP, Anti-SSX2IP, Anti-KIAA0923, Anti-SSX2-interacting protein, Anti-Afadin DIL domain-interacting protein, Anti-Afadin- and alpha-actinin-binding protein
Supplier-Nr: A311-216A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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