Notch2 Antibody AbVantage(TM) Pack

Notch2 Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-736A 1 pack -

3 - 9 business days*

617.00€
 
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1... more
Product information "Notch2 Antibody AbVantage(TM) Pack"
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in bone remodeling and homeostasis. In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation. Positively regulates self-renewal of liver cancer cells (PubMed:25985737). [The UniProt Consortium]
Keywords: Anti-Notch2, Anti-NOTCH-2, Anti-neurogenic locus notch homolog protein 2, Anti-AGS2.
Supplier: Bethyl Laboratories
Supplier-Nr: A310-736A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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