Notch1 Antibody AbVantage(TM) Pack

Notch1 Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-672A 1 pack -

3 - 9 business days*

617.00€
 
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1... more
Product information "Notch1 Antibody AbVantage(TM) Pack"
Protein function: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4+ and CD8+ cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. May enhance HIF1A function by sequestering HIF1AN away from HIF1A. Required for the THBS4 function in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). [The UniProt Consortium]
Keywords: Anti-TAN1, Anti-NOTCH1
Supplier: Bethyl Laboratories
Supplier-Nr: A310-672A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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-10 %
Offer
Anti-NOTCH1 Anti-NOTCH1
530.00€ * 477.00€ *
-10 %
Offer
Anti-NOTCH1 Anti-NOTCH1
314.00€ * 282.60€ *
-10 %
Offer
Anti-NOTCH1 Anti-NOTCH1
314.00€ * 282.60€ *
-10 %
Offer
Anti-NOTCH1 Anti-NOTCH1
314.00€ * 282.60€ *
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