JMJD1A/JHDM2A Antibody AbVantage(TM) Pack

JMJD1A/JHDM2A Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-540A 1 pack -

3 - 9 business days

Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3,... more
Product information "JMJD1A/JHDM2A Antibody AbVantage(TM) Pack"
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a central role in histone code. Preferentially demethylates mono- and dimethylated H3 'Lys-9' residue, with a preference for dimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. Demethylation of Lys residue generates formaldehyde and succinate. Involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. Involved in spermatogenesis by regulating expression of target genes such as PRM1 and TMP1 which are required for packaging and condensation of sperm chromatin. Involved in obesity resistance through regulation of metabolic genes such as PPARA and UCP1. [The UniProt Consortium]
Keywords: Anti-KDM3A, Anti-JHDM2A, EC=1.14.11.-, Anti-Lysine-specific demethylase 3A, Anti-Jumonji domain-containing protein 1A, Anti-JmjC domain-containing histone demethylation protein 2A
Supplier: Bethyl Laboratories
Supplier-Nr: A310-540A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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