Product information "INO80 Antibody AbVantage(TM) Pack"
Protein function: DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair, according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle. [The UniProt Consortium]
Anti-INO80, Anti-INO80A, Anti-hINO80, EC=188.8.131.52, Anti-DNA helicase INO80, Anti-INO80 complex subunit A, Anti-Putative DNA helicase INO80 complex homolog 1