Dicer Antibody AbVantage(TM) Pack

Dicer Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-686A 1 pack -

3 - 9 business days*

Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short... more
Product information "Dicer Antibody AbVantage(TM) Pack"
Protein function: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA- induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes. [The UniProt Consortium]
Keywords: Anti-DICER, Anti-DICER1, EC=, Anti-Helicase MOI, Anti-Endoribonuclease Dicer, Anti-Helicase with RNase motif
Supplier: Bethyl Laboratories
Supplier-Nr: A310-686A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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