CLASP2 Antibody AbVantage(TM) Pack

CLASP2 Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-768A 1 pack -

3 - 9 business days*

617.00€
 
Protein function: Microtubule plus-end tracking protein that promotes the stabilization of... more
Product information "CLASP2 Antibody AbVantage(TM) Pack"
Protein function: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2- dependent stabilization of microtubules at the cell cortex. [The UniProt Consortium]
Keywords: Anti-CLASP2, Anti-hOrbit2, Anti-KIAA0627, Anti-Protein Orbit homolog 2, Anti-CLIP-associating protein 2, Anti-Cytoplasmic linker-associated protein 2
Supplier: Bethyl Laboratories
Supplier-Nr: A310-768A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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