ASF Antibody AbVantage(TM) Pack

ASF Antibody AbVantage(TM) Pack
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A310-725A 1 pack -

3 - 9 business days

Protein function: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and... more
Product information "ASF Antibody AbVantage(TM) Pack"
Protein function: Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'- CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. Isoform ASF-2 and isoform ASF-3 act as splicing repressors. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway. [The UniProt Consortium]
Keywords: Anti-ASF, Anti-ASF-1, Anti-SRSF1, Anti-Alternative-splicing factor 1, Anti-Serine/arginine-rich splicing factor 1, Anti-Splicing factor, arginine/serine-rich 1, Anti-pre-mRNA-splicing factor SF2, P33 subunit
Supplier: Bethyl Laboratories
Supplier-Nr: A310-725A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: synthetic peptide
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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