Anti-ZP3, CT (ZP3, ZP3A, ZP3B, ZPC, Zona pellucida sperm-binding protein 3, Sperm receptor, ZP3A/ZP3

Anti-ZP3, CT (ZP3, ZP3A, ZP3B, ZPC, Zona pellucida sperm-binding protein 3, Sperm receptor, ZP3A/ZP3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
044404-FITC.200 200 µl - -

4 - 22 business days

696.00€
 
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is... more
Product information "Anti-ZP3, CT (ZP3, ZP3A, ZP3B, ZPC, Zona pellucida sperm-binding protein 3, Sperm receptor, ZP3A/ZP3"
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus, however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: Anti-ZP3, Anti-ZP3A
Supplier: United States Biological
Supplier-Nr: 044404-FITC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: ZP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-380 amino acids from the C-terminal region of human ZP3.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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