Anti-ZNF385A, NT (ZNF385A, HZF, RZF, ZNF385, Zinc finger protein 385A, Hematopoietic zinc finger pro

Anti-ZNF385A, NT (ZNF385A, HZF, RZF, ZNF385, Zinc finger protein 385A, Hematopoietic zinc finger pro
Item number Size Datasheet Manual SDS Delivery time Quantity Price
044214-APC.200 200 µl - -

4 - 22 business days

696.00€
 
Protein function: RNA-binding protein that affects the localization and the translation of a... more
Product information "Anti-ZNF385A, NT (ZNF385A, HZF, RZF, ZNF385, Zinc finger protein 385A, Hematopoietic zinc finger pro"
Protein function: RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti- proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation. [The UniProt Consortium]
Keywords: Anti-HZF, Anti-ZNF385A, Anti-Zinc finger protein 385A, Anti-Retinal zinc finger protein, Anti-Hematopoietic zinc finger protein
Supplier-Nr: 044214-APC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human
Immunogen: ZNF385A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ZNF385A.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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