Anti-ZNF198 (Zinc Finger MYM-type Protein 2, Fused in Myeloproliferative Disorders Protein, Rearrang

Anti-ZNF198 (Zinc Finger MYM-type Protein 2, Fused in Myeloproliferative Disorders Protein, Rearrang
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Z0741-40E.100 100 µg - -

1 - 19 business days

449.00€
 
ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown.... more
Product information "Anti-ZNF198 (Zinc Finger MYM-type Protein 2, Fused in Myeloproliferative Disorders Protein, Rearrang"
ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1-1ug/ml, Immunohistochemistry (paraffin): 10ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Mouse skeletal muscle lysate, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Zinc finger protein 198, Anti-Zinc finger MYM-type protein 2, Anti-Fused in myeloproliferative disorders protein, Anti-Rearranged in atypical myeloproliferative disorder protein
Supplier: United States Biological
Supplier-Nr: Z0741-40E

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Dog, Human, Monkey, Mouse
Immunogen: Synthetic peptide corresponding to aa1250-1300 of human Zinc finger protein 198.
Format: Affinity Purified

Database Information

UniProt ID : Q9UBW7 | Find alternatives
Gene ID GeneID 7750 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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