Anti-ZFYVE19

Item number	Size	Manual	Delivery time	Price
A301-808A-T	20 µl (2 blots)	-	3 - 9 business days*	131.00€
A301-808A-M	100 µl (10 blots)	-	3 - 9 business days*	313.00€
A301-808A	100 µl (100 µg)	-	3 - 9 business days*	465.00€

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Protein function: Key regulator of abscission step in cytokinesis: part of the cytokinesis... more

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Product information "Anti-ZFYVE19"

Protein function: Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. [The UniProt Consortium]

Keywords:	Anti-ANCHR, Anti-ZFYVE19, Anti-MLL partner containing FYVE domain, Anti-Abscission/NoCut checkpoint regulator, Anti-Zinc finger FYVE domain-containing protein 19
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-808A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Reactivity:	Human (Expected: Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-808A-T maps to a region between residue 425 and 471 of human zinc finger, FYVE domain containing 19 using the numbering given in entry NP_001070736.1 (GeneID 84936).
Format:	Antigen Affinity Purified