Product information "Anti-ZFP57, ID (ZFP57, C6orf40, ZNF698, Zinc finger protein 57 homolog, Zinc finger protein 698) (Az"
Protein function: Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element. Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions. Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. [The UniProt Consortium]
Anti-ZFP57, Anti-Zfp-57, Anti-C6orf40, Anti-Zinc finger protein 698, Anti-Zinc finger protein 57 homolog