Anti-ZFP36L2, ID (ZFP36L2, BRF2, ERF2, RNF162C, TIS11D, Zinc finger protein 36, C3H1 type-like 2, Bu

Anti-ZFP36L2, ID (ZFP36L2, BRF2, ERF2, RNF162C, TIS11D, Zinc finger protein 36, C3H1 type-like 2, Bu
Item number Size Datasheet Manual SDS Delivery time Quantity Price
044063-APC.200 200 µl - -

4 - 22 business days

696.00€
 
Protein function: mRNA-binding protein that plays a key role in self- renewal of erythroid cells... more
Product information "Anti-ZFP36L2, ID (ZFP36L2, BRF2, ERF2, RNF162C, TIS11D, Zinc finger protein 36, C3H1 type-like 2, Bu"
Protein function: mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation. [The UniProt Consortium]
Keywords: Anti-BRF2, Anti-ERF-2, Anti-ZFP36L2, Anti-ZFP36-like 2, Anti-Protein TIS11D, Anti-EGF-response factor 2, Anti-Butyrate response factor 2, Anti-Zinc finger protein 36, C3H1 type-like 2
Supplier-Nr: 044063-APC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: ZFP36L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human ZFP36L2.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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