Product information "Anti-ZBTB7B, ID (Zinc finger and BTB domain-containing protein 7B,ZBTB7B,ZBTB15, ZFP67, ZNF857B) (Az"
Protein function: Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes. [The UniProt Consortium]
Anti-ZBTB15, Anti-hcKrox, Anti-ZBTB7B, Anti-Zfp-67, Anti-Zinc finger protein 857B, Anti-Zinc finger protein Th-POK, Anti-Zinc finger protein 67 homolog, Anti-Krueppel-related zinc finger protein cKrox, Anti-T-helper-inducing POZ/Krueppel-like factor