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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Z0330-25.100 | 100 µg | - | - |
3 - 19 business days* |
629.00€
|
ZBTB2 is a member of the POK (POZ domain Krüppel-like zinc finger) family and plays an important... more
Product information "Anti-ZBTB2 (Zinc Finger and BTB Domain-containing Protein 2, KIAA1483, ZNF437)"
ZBTB2 is a member of the POK (POZ domain Krüppel-like zinc finger) family and plays an important role in cell cycle regulation. It is a transcription factor and a potent repressor of the ARF-HDM2-p53-p21 pathway. ZBTB2 represses the transcription of the p21, p53 and ARF genes and activates HDM2 gene. ZBTB2 and Sp1 compete with each other in binding to the GC-box 5:6 elements and the two p53 binding elements. ZBTB2 directly interacted with p53 via its zinc fingers, inhibiting p53 binding and repressing transcription activation by p53. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 2-5ug/ml, Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-Zinc finger and BTB domain-containing protein 2 |
Supplier: | United States Biological |
Supplier-Nr: | Z0330-25 |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | dog, horse, human, monkey, mouse, rat |
Immunogen: | Synthetic peptide corresponding to aa450 to 500 of human ZBTB2. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K10489 | Matching products |
UniProt ID : | Q8N680 | Matching products |
Gene ID | GeneID 57621 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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