Anti-YTHDC2

Anti-YTHDC2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-025A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A303-025A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs... more
Product information "Anti-YTHDC2"
Protein function: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs affecting the translation efficiency and mRNA abundance of its targets (PubMed:26318451). Is required for proper spermatocyte development. M6A is a modification present at internal sites of mRNAs and some non- coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:26318451). When associated with MEIOC, binds transcripts that regulate the mitotic cell cycle inhibiting progression into metaphase, thereby allowing meiotic prophase to proceed normally. [The UniProt Consortium]
Keywords: Anti-YTHDC2, EC=3.6.4.13, Anti-YTH domain-containing protein 2, Anti-Probable ATP-dependent RNA helicase YTHDC2
Supplier: Bethyl Laboratories
Supplier-Nr: A303-025A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan)
Immunogen: synthetic peptide. The epitope recognized by A303-025A-T maps to a region between residue 1200 and 1250 of human YTH Domain Containing 2 using the numbering given in entry NP_073739.3 (GeneID 64848).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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