Anti-XRN1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-443A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-443A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the... more
Product information "Anti-XRN1"
Protein function: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA. Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS). [The UniProt Consortium]
Keywords: Anti-SEP1, Anti-XRN1, EC=3.1.13.-, Anti-5'-3' exoribonuclease 1, Anti-Strand-exchange protein 1 homolog
Supplier: Bethyl Laboratories
Supplier-Nr: A300-443A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: bovine, dog, horse, orangutan, rhesus monkey, chimpanzee, tasmanian devil, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A300-443A-T maps to a region between residue 1650 and the C-terminus (residue 1706) of human 5'-3' Exoribonuclease 1 using the numbering given in TrEMBL entry Q6MZS8 (GeneID 54464).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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