Anti-WWP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-936A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-936A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2... more

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Product information "Anti-WWP2"

Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation- induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation. [The UniProt Consortium]

Keywords:	Anti-AIP2, Anti-WWP2, EC=2.3.2.26, Anti-WW domain-containing protein 2, Anti-Atrophin-1-interacting protein 2, Anti-HECT-type E3 ubiquitin transferase WWP2, Anti-NEDD4-like E3 ubiquitin-protein ligase WWP2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-936A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, primates, white-tufted-ear marmoset, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-936A-T maps to a region between residue 200 and 250 of human WW Domain Containing E3 Ubiquitin Protein Ligase 2 using the numbering given in entry NP_008945.2 (GeneID 11060).
Format:	Antigen Affinity Purified