Anti-VEGFA (suvemcitug biosimilar) mAb

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
DIM-BME100682.50	50 µg		-	-	7 - 16 business days*		120.00€
DIM-BME100682.100	100 µg		-	-	7 - 16 business days*		237.00€

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Research use only. Protein function: Growth factor active in angiogenesis, vasculogenesis and... more

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Product information "Anti-VEGFA (suvemcitug biosimilar) mAb"

Research use only. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437). [The UniProt Consortium]

Keywords:	APX003,APX-003,BD0801,BD-0801,TK001,TK-001,Sevacizumab (not WHO assigned INN), Anti-VPF, Anti-VEGF, Anti-VEGFA, Anti-VEGF-A, Anti-Vascular permeability factor, Anti-Vascular endothelial growth factor A
Supplier:	DIMA
Supplier-Nr:	BME100682

Properties

Antibody Type:	Monoclonal
Conjugate:	No
Species reactivity:	human
Format:	Lyophilized

Database Information

KEGG ID :	K05448 \| Matching products
UniProt ID :	P15692 \| Matching products
Gene ID :	GeneID 7422 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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