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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
REV-31-1277-00-R100 | 100 µl | - | - |
3 - 9 business days* |
483.00€
|
Recombinant Antibody. This antibody reacts to human VEGFA. Applications: WB, IHC. Source: Rabbit.... more
Product information "Anti-VEGFA (human), Rabbit Monoclonal (RM391)"
Recombinant Antibody. This antibody reacts to human VEGFA. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. VEGF (vascular endothelial growth factor) is a 45 kDa homodimeric disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis and vascular permeability. The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process. VEGF-A binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF-A is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
Keywords: | Vascular Endothelial Growth Factor A, Vascular Permeability Factor |
Supplier: | RevMAb Biosciences |
Supplier-Nr: | 31-1277-00 |
Properties
Application: | WB, IHC |
Antibody Type: | Monoclonal |
Clone: | RM391 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Format: | Purified |
Database Information
KEGG ID : | K05448 | Matching products |
UniProt ID : | P15692 | Matching products |
Gene ID | GeneID 7422 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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