Anti-V5 tag, clone E10

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG62340.100	100 µg		-	-	6 - 14 business days*		396.00€

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Protein function: Plays an essential role in the inhibition of host immune response. Prevents the... more

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Product information "Anti-V5 tag, clone E10"

Protein function: Plays an essential role in the inhibition of host immune response. Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway. Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state. Efficiently blocks type I IFN signaling following infection by behaving as a substrate receptor for CUL4-DDB1 E3 ligase complex and targeting host STAT1 for proteasomal degradation. [The UniProt Consortium]

Keywords:	Anti-Non-structural protein V
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG62340

Properties

Application:	ELISA, ICC, IF, IHC, IP, WB
Antibody Type:	Monoclonal
Clone:	E10 = V4RR
Conjugate:	No
Host:	Mouse
Species reactivity:	other
Immunogen:	GKPIPNPLLGLDST (V5) synthetic peptide conjugated to KLH
Format:	Purified