Anti-USP9X

Anti-USP9X
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB16307.100 100 µl -

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299.00€
 
WB 1:500 - 1:2000. Protein function: Deubiquitinase involved both in the processing of ubiquitin... more
Product information "Anti-USP9X"
WB 1:500 - 1:2000. Protein function: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys- 29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions (PubMed:25944111). Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration (PubMed:16322459, PubMed:18254724, PubMed:19135894, PubMed:24607389). Regulates cellular clock function by enhancing the protein stability and transcriptional activity of the core circadian protein ARNTL/BMAL1 via its deubiquitinating activity (PubMed:29626158). [The UniProt Consortium]
Keywords: Anti-hFAM, Anti-DFFRX, EC=3.4.19.12, Anti-Fat facets in mammals, Anti-Ubiquitin thioesterase FAF-X, Anti-Deubiquitinating enzyme FAF-X, Anti-Fat facets protein-related, X-linked, Anti-Ubiquitin-specific protease 9, X chromosome, USP9X Polyclonal Antibody
Supplier: Antibody Genie
Supplier-Nr: CAB16307

Properties

Application: WB
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human USP9X
MW: 292 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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