Protein function: Hydrolase that deubiquitinates monoubiquitinated target proteins such as histone H2A and H2B. Required for proper progression through S phase and subsequent mitotic entry. May regulate the DNA damage response (DDR) checkpoint through deubiquitination of H2A at DNA damage sites. Associates with the chromatin. [The UniProt Consortium]
synthetic peptide. The epitope recognized by A301-540A-T maps to a region between residue 325 and 375 of human ubiquitin specific protease 3 using the numbering given in entry AAD42992.1 (GeneID 9960).