Anti-USP16

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-615A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-615A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific... more

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Product information "Anti-USP16"

Protein function: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T- lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. [The UniProt Consortium]

Keywords:	Anti-MSTP039, Anti-Ubiquitin thioesterase 16, Anti-Deubiquitinating enzyme 16, Anti-Ubiquitin-processing protease UBP-M, Anti-Ubiquitin carboxyl-terminal hydrolase 16, Anti-Ubiquitin-specific-processing protease 16
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-615A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine)
Immunogen:	synthetic peptide. The epitope recognized by A301-615A-T maps to a region between residue 225 and 275 of human ubiquitin specific peptidase 16 using the numbering given in entry NP_006438.1 (GeneID 10600).
Format:	Antigen Affinity Purified