Anti-UBR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-988A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-988A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway.... more

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Product information "Anti-UBR1"

Protein function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth. [The UniProt Consortium]

Keywords:	Anti-UBR1, EC=2.3.2.27, Anti-N-recognin-1, Anti-E3 ubiquitin-protein ligase UBR1, Anti-Ubiquitin-protein ligase E3-alpha-1, Anti-Ubiquitin-protein ligase E3-alpha-I, Anti-RING-type E3 ubiquitin transferase UBR1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-988A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, dog, horse, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, african elephant, naked mole rat, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A302-988A-T maps to a region between residue 1125 and 1175 of human Ubiquitin Protein Ligase E3 Component n-Recognin 1 using the numbering given in entry NP_777576.1 (GeneID 197131).
Format:	Antigen Affinity Purified