Anti-Ubiquitin (Clone 6C11-B3)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13723-50 50 µg -

6 - 10 business days*

241.00€
Cay13723-200 200 µg -

6 - 10 business days*

489.00€
 
Ubiquitin is a regulatory protein encoded by three gene classes in humans, which code for fusion... more
Product information "Anti-Ubiquitin (Clone 6C11-B3)"
Ubiquitin is a regulatory protein encoded by three gene classes in humans, which code for fusion proteins between ubiquitin and zinc-finger proteins, ribosomal proteins, or ubiquitin repeats that are cleaved by esterases to release monomeric ubiquitin. It is ubiquitously expressed and highly conserved among eukaryotic species. Ubiquitin is conjugated to misfolded, abnormal, short-lived, or foreign proteins by ubiquitin-conjugating enzymes (E2) and substrate-specific ubiquitin ligases (E3) to target them for degradation by the 26S proteasome or lysosome. It is also conjugated to proteins to modify cell signaling through regulation of protein-protein interactions, activity, or subcellular localization. Dysregulation of ubiquitination has been implicated in the pathogenesis of neurodegenerative diseases, including Parkinson's and Alzheimer's diseases. Cayman's Ubiquitin Monoclonal Antibody (Clone 6C11-B3) can be used for ELISA, immunocytochemistry (ICC), immunofluorescence (IF), and Western blot (WB) applications. The antibody recognizes ubiquitin at ~10 kDa from human samples.Immunogen: Bovine ubiquitin conjugated to KLH. Clone Designation: 6C11-B3. MW: ~10 kDa. Formulation: (Request formulation change), 50 or 200 µg of protein G-affinity purified monoclonal antibody. Storage Buffer: PBS, pH 7.4, with 50% glycerol and 0.09% sodium azide. Host: Mouse. Isotype: IgG2akappa. Applications: ELISA, ICC, IF, WB. Cross Reactivity: (+) Ubiquitin. UniProt Accession #: P0CG53. Origin: Animal/Mouse.
Supplier: Cayman Chemical
Supplier-Nr: 13723

Properties

Application: WB, ELISA
Antibody Type: Monoclonal
Clone: 6C11-B3
Conjugate: No
Host: Mouse
Species reactivity: bovine
Immunogen: native bovine ubiquitin conjugated to KLH
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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