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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in... more
Product information "Anti-TYR"
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. Protein function: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) to indole-5,6 quinone. [The UniProt Consortium]
Keywords: | Anti-TYR, Anti-LB24-AB, Anti-SK29-AB, Anti-Tyrosinase, EC=1.14.18.1, Anti-Monophenol monooxygenase, Anti-Tumor rejection antigen AB, TYR Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-64747 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat |
Immunogen: | Recombinant protein of human TYR |
Database Information
KEGG ID : | K00505 | Matching products |
UniProt ID : | P14679 | Matching products |
Gene ID | GeneID 7299 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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