Anti-TSLP (Thymic Stromal Lymphopoietin)

Anti-TSLP (Thymic Stromal Lymphopoietin)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T9127-03.100 100 µg - -

3 - 19 business days

503.00€
 
Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable... more
Product information "Anti-TSLP (Thymic Stromal Lymphopoietin)"
Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Immunohistochemistry: 2.5ug/ml, Western Blot: 0.5-1ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: A20 Cell Lysate (WB), Human Brain Tissue (IHC), Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Thymic stromal lymphopoietin
Supplier: United States Biological
Supplier-Nr: T9127-03

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: 19 amino acid peptide from near the center of human TSLP.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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