Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V8143-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
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NSJ-V8143-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
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Protein function: Indispensable for the control of thyroid structure and metabolism. [The UniProt Consortium] The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Keywords: | Anti-TSHB, Anti-TSH-B, Anti-TSH-beta, Anti-Thyrotropin alfa, Anti-Thyrotropin beta chain, Anti-Thyrotropin subunit beta, Anti-Thyroid-stimulating hormone subunit beta |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V8143 |
Properties
Application: | IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | TSHb/1317 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | A recombinant human partial protein |
Format: | Purified |
Database Information
KEGG ID : | K05251 | Matching products |
UniProt ID : | P01222 | Matching products |
Gene ID | GeneID 7252 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!